NASHVILLE, Tenn. (AP) -- The Tennessee Titans are unbeaten no more. Brett Favre and the New York Jets served notice they will be a factor in the AFC this season.

Favre threw two touchdown passes, Leon Washington ran for two scores and the Jets routed the Titans 34-13, snapping the 13-game regular-season winning streak by the Titans.

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Patriots 48, Dolphins 28

MIAMI -- Matt Cassel threw for 415 yards, Randy Moss caught three touchdown passes and the resilient Patriots won a shootout.

Cowboys 35, 49ers 22

IRVING, Texas -- Bottled up all season, and his frustration starting to show, Terrell Owens broke out with seven catches for 213 yards to help Dallas beat San Francisco.

Ravens 36, Eagles 7

BALTIMORE -- Pulled after an awful first half, Donovan McNabb watched from the sideline as the Baltimore Ravens beat the Philadelphia Eagles, presenting first-year coach John Harbaugh with a lopsided victory over the team he served as an assistant for 10 years.

Bills 54, Chiefs 31

KANSAS CITY, Mo. -- Trent Edwards threw for two touchdowns, ran for two others and Buffalo scored more points than had ever been scored against Kansas City.

Texans 16, Browns 6

CLEVELAND -- Sage Rosenfels passed for 275 yards and a touchdown, and Kris Brown kicked three field goals as Houston snapped an eight-game losing streak outside Texas.

Bears 27, Rams 3

ST. LOUIS -- Rookie Matt Forte had a season-high 132 yards rushing and scored on two long runs, and Marc Bulger lasted only five plays before sustaining a concussion against a defense that had five sacks.

Buccaneers 38, Lions 20

DETROIT -- Tampa Bay fell behind the winless Lions by 17 points, then scored five unanswered touchdowns.

Giants 37, Cardinals 29

GLENDALE, Ariz. -- Eli Manning threw for three touchdowns in his return to the scene of his Super Bowl MVP performance and the Giants beat Arizona to snap the Cardinals' seven-game home winning streak.

Oakland 31, Denver 10

DENVER -- Ashley Lelie, who forced a trade out of Denver in 2006 after a bitter holdout, returned to Invesco Field helped lead Oakland to a stunning win over the Broncos by catching a touchdown pass and setting up another with a 51-yard reception.

Falcons 45, Panthers 28

ATLANTA -- Michael Turner scored four touchdowns and rookie Harry Douglas scored his first career TD as Atlanta won a key NFC South showdown.

Redskins 20, Seahawks 17

SEATTLE -- Clinton Portis ran for 143 yards on 29 carries, including key ones late that helped preserve the Redskins' victory.