PARIS (AP) -- Needing one point for an upset win over Justine Henin at the French Open, Sam Stosur wavered, hitting a double-fault.
The Australian took a deep breath and tried again. This time she launched a confident serve into the corner, setting her up for an overhead slam to seal the biggest victory of her career.
Stosur sidelined Henin 2-6, 6-1, 6-4 in the fourth round Monday, ending the four-time French Open champion's streak of 24 consecutive victories at Roland Garros. Stosur's opponent in the quarterfinals will be top-ranked Serena Williams, who beat Shahar Peer 6-2, 6-2.
"Obviously beating Justine is going to give me lot and lots of confidence," said Stosur, seeded No. 7. "It's a great achievement for me, but it's not over yet. I'm just in the quarters and going to play the No. 1 player in the world next."
Another four-time champion, Rafael Nadal, advanced by beating No. 24-seeded Thomaz Bellucci 6-2, 7-5, 6-4. Nadal, who lost in the fourth round in 2009, has yet to drop a set this year and will next play fellow Spaniard Nicolas Almagro, seeded 19th.
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No. 3-seeded Novak Djokovic eliminated the last American in the men's draw, beating Robby Ginepri 6-4, 2-6, 6-1, 6-2.
No. 4 Jelena Jankovic and unseeded Yaroslava Shvedova won in straight sets and will meet in the quarterfinals.
Henin's defeat was her first in the tournament since 2004. She was seeded 22nd playing at Roland Garros for the first time since ending a 20-month retirement, and looked like a title contender in the early rounds.
"I just wanted so much that the adventure could continue," Henin said.
Williams advanced easily, looking shaky only after her fourth-round victory, when she tried to speak French to the crowd.
"I get so nervous," she told the interviewer with a giggle in English when she was done. Otherwise, she advanced smoothly to the quarterfinals.
"I seem to always be able to turn it up during this particular stage," Williams said. "Hopefully I turn it up again."
She complained of dizziness from a cold following a seesaw three-set win in her previous match, but the only wobble against the No. 18-seeded Peer came at the start. Williams lost the first seven points, then swept nine in a row.
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From 2-all, Williams won five consecutive games to take charge of the match.
Afterward, she was interviewed courtside by former French player Cedric Pioline.
"I love Paris," she told the crowd in French. "My game is better. I hope I'm going to win."
Stosur's win spoiled the prospect of a showdown between longtime rivals Williams and Henin. Instead, Williams will meet Stosur.
"You can never underestimate anyone, and Sam is actually a wonderful clay-court player," Williams said. "She's someone you can't overlook."
Against Djokovic, Ginepri was serving at love-1 in the third set when he went down face-first chasing a shot. He made the most of his awkward court position by doing push-ups, but lost the next two points to lose serve, and won only three games the rest of the way.
"I felt a little stupid slipping and falling on my face, so I tried to get the crowd back to my side," Ginepri said. "Maybe that took a little bit of my focus away doing that. I'll probably never do push-ups again on court."
Djokovic's next opponent will be No. 22 Jurgen Melzer, a first-time Grand Slam quarterfinalist playing in his 32nd major event. The Austrian advanced by beating qualifier Teimuraz Gabashvili 7-6 (6), 4-6, 6-1, 6-4.
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Almagro beat fellow Spaniard Fernando Verdasco 6-1, 4-6, 6-1, 6-4.
Jankovic committed only 11 unforced errors and defeated No. 23 Daniela Hantuchova 6-4, 6-2. Shvedova became a Grand Slam quarterfinalist for the first time by beating wild card Jarmila Groth 6-4, 6-3.